Basbaum Lab

Publications

1. Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Stein RM, Craik V, Tran NK, Ganapathy S, Liu F, Shiimura Y, Tong F, Ho TC, Radchenko DS, Moroz YS, Rosado SR, Bhardwaj K, Benitez J, Liu Y, Kandasamy H, Normand C, Semache M, Sabbagh L, Glenn I, Irwin JJ, Kumar KK, Makriyannis A, Basbaum AI, Shoichet BK. Large library docking for cannabinoid-1 receptor agonists with reduced side effects. bioRxiv. 2024 Feb 28. View on PubMed
2. Gahbauer S, DeLeon C, Braz JM, Craik V, Kang HJ, Wan X, Huang XP, Billesbølle CB, Liu Y, Che T, Deshpande I, Jewell M, Fink EA, Kondratov IS, Moroz YS, Irwin JJ, Basbaum AI, Roth BL, Shoichet BK. Docking for EP4R antagonists active against inflammatory pain. Nat Commun. 2023 Dec 06; 14(1):8067. View on PubMed
3. Basbaum AI, Jensen TS, Keefe FJ. Fifty years of pain research and clinical advances: highlights and key trends. Pain. 2023 Nov 01; 164(11S):S11-S15. View on PubMed
4. Davis KD, Basbaum AI, Bushnell MC, Yarnitsky D, Fields HL. International Association for the Study of Pain publications over the 50-year span. Pain. 2023 Nov 01; 164(11S):S27-S30. View on PubMed
5. Fassett MS, Braz JM, Castellanos CA, Salvatierra JJ, Sadeghi M, Yu X, Schroeder AW, Caston J, Munoz-Sandoval P, Roy S, Lazarevsky S, Mar DJ, Zhou CJ, Shin JS, Basbaum AI, Ansel KM. IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis. Sci Immunol. 2023 10 20; 8(88):eabi6887. View on PubMed
6. Linguiti S, Vogel JW, Sydnor VJ, Pines A, Wellman N, Basbaum A, Eickhoff CR, Eickhoff SB, Edwards RR, Larsen B, McKinstry-Wu A, Scott JC, Roalf DR, Sharma V, Strain EC, Corder G, Dworkin RH, Satterthwaite TD. Functional imaging studies of acute administration of classic psychedelics, ketamine, and MDMA: Methodological limitations and convergent results. Neurosci Biobehav Rev. 2023 Nov; 154:105421. View on PubMed
7. Braz JM, Hamel K, Craik V, Rodriguez-Rosado S, Bhardwaj K, Jewell M, Bieri G, Villeda SA, Basbaum AI. Pain and Itch Processing in Aged Mice. J Pain. 2024 Jan; 25(1):53-63. View on PubMed
8. Ahanonu B, Crowther A, Kania A, Casillas MR, Basbaum A. Long-term optical imaging of the spinal cord in awake, behaving animals. bioRxiv. 2023 May 24. View on PubMed
9. Singh I, Seth A, Billesbølle CB, Braz J, Rodriguiz RM, Roy K, Bekele B, Craik V, Huang XP, Boytsov D, Pogorelov VM, Lak P, O'Donnell H, Sandtner W, Irwin JJ, Roth BL, Basbaum AI, Wetsel WC, Manglik A, Shoichet BK, Rudnick G. Structure-based discovery of conformationally selective inhibitors of the serotonin transporter. Cell. 2023 05 11; 186(10):2160-2175.e17. View on PubMed
10. Weinrich JA, Liu CD, Jewell ME, Andolina CR, Bernstein MX, Benitez J, Rodriguez-Rosado S, Braz JM, Maze M, Nemenov MI, Basbaum AI. Paradoxical increases in anterior cingulate cortex activity during nitrous oxide-induced analgesia reveal a signature of pain affect. bioRxiv. 2023 Apr 03. View on PubMed
11. Fink EA, Xu J, Hübner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, Chen G, Liu Z, Jacobson MP, Irwin JJ, Bouvier M, Du Y, Shoichet BK, Basbaum AI, Gmeiner P. Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor. Science. 2022 09 30; 377(6614):eabn7065. View on PubMed
12. Yue WWS, Yuan L, Braz JM, Basbaum AI, Julius D. TRPV1 drugs alter core body temperature via central projections of primary afferent sensory neurons. Elife. 2022 08 15; 11. View on PubMed
13. Basbaum A. History of Spinal Cord "Pain" Pathways Including the Pathways Not Taken. Front Pain Res (Lausanne). 2022; 3:910954. View on PubMed
14. Henn AT, Larsen B, Frahm L, Xu A, Adebimpe A, Scott JC, Linguiti S, Sharma V, Basbaum AI, Corder G, Dworkin RH, Edwards RR, Woolf CJ, Habel U, Eickhoff SB, Eickhoff CR, Wagels L, Satterthwaite TD. Structural imaging studies of patients with chronic pain: an anatomical likelihood estimate meta-analysis. Pain. 2023 01 01; 164(1):e10-e24. View on PubMed
15. Yu X, Ton AN, Niu Z, Morales BM, Chen J, Braz J, Lai MH, Barruet E, Liu H, Cheung K, Ali S, Chan T, Bigay K, Ho J, Nikolli I, Hansberry S, Wentworth K, Kriegstein A, Basbaum A, Hsiao EC. ACVR1-activating mutation causes neuropathic pain and sensory neuron hyperexcitability in humans. Pain. 2023 01 01; 164(1):43-58. View on PubMed
16. Levit Kaplan A, Strachan RT, Braz JM, Craik V, Slocum S, Mangano T, Amabo V, O'Donnell H, Lak P, Basbaum AI, Roth BL, Shoichet BK. Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor. J Med Chem. 2022 03 10; 65(5):4201-4217. View on PubMed
17. Alon A, Lyu J, Braz JM, Tummino TA, Craik V, O'Meara MJ, Webb CM, Radchenko DS, Moroz YS, Huang XP, Liu Y, Roth BL, Irwin JJ, Basbaum AI, Shoichet BK, Kruse AC. Structures of the σ2 receptor enable docking for bioactive ligand discovery. Nature. 2021 Dec; 600(7890):759-764. View on PubMed
18. Kuhn JA, Vainchtein ID, Braz J, Hamel K, Bernstein M, Craik V, Dahlgren MW, Ortiz-Carpena J, Molofsky AB, Molofsky AV, Basbaum AI. Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice. Elife. 2021 10 15; 10. View on PubMed
19. Wercberger R, Braz JM, Weinrich JA, Basbaum AI. Pain and itch processing by subpopulations of molecularly diverse spinal and trigeminal projection neurons. Proc Natl Acad Sci U S A. 2021 07 13; 118(28). View on PubMed
20. Löken LS, Braz JM, Etlin A, Sadeghi M, Bernstein M, Jewell M, Steyert M, Kuhn J, Hamel K, Llewellyn-Smith IJ, Basbaum A. Contribution of dorsal horn CGRP-expressing interneurons to mechanical sensitivity. Elife. 2021 06 01; 10. View on PubMed
21. Wang TA, Chen C, Huang F, Feng S, Tien J, Braz JM, Basbaum AI, Jan YN, Jan LY. TMEM16C is involved in thermoregulation and protects rodent pups from febrile seizures. Proc Natl Acad Sci U S A. 2021 05 18; 118(20). View on PubMed
22. Yu X, Basbaum A, Guan Z. Contribution of colony-stimulating factor 1 to neuropathic pain. Pain Rep. 2021; 6(1):e883. View on PubMed
23. Braz JM, Dembo T, Charruyer A, Ghadially R, Fassett MS, Basbaum AI. Genetic priming of sensory neurons in mice that overexpress PAR2 enhances allergen responsiveness. Proc Natl Acad Sci U S A. 2021 02 23; 118(8). View on PubMed
24. Xu A, Larsen B, Henn A, Baller EB, Scott JC, Sharma V, Adebimpe A, Basbaum AI, Corder G, Dworkin RH, Edwards RR, Woolf CJ, Eickhoff SB, Eickhoff CR, Satterthwaite TD. Brain Responses to Noxious Stimuli in Patients With Chronic Pain: A Systematic Review and Meta-analysis. JAMA Netw Open. 2021 01 04; 4(1):e2032236. View on PubMed
25. Alvaro CG, Braz JM, Bernstein M, Hamel KA, Craik V, Yamanaka H, Basbaum AI. Hippocalcin-like 4, a neural calcium sensor, has a limited contribution to pain and itch processing. PLoS One. 2020; 15(2):e0226289. View on PubMed
26. Xu A, Larsen B, Baller EB, Scott JC, Sharma V, Adebimpe A, Basbaum AI, Dworkin RH, Edwards RR, Woolf CJ, Eickhoff SB, Eickhoff CR, Satterthwaite TD. Convergent neural representations of experimentally-induced acute pain in healthy volunteers: A large-scale fMRI meta-analysis. Neurosci Biobehav Rev. 2020 05; 112:300-323. View on PubMed
27. Yu X, Liu H, Hamel KA, Morvan MG, Yu S, Leff J, Guan Z, Braz JM, Basbaum AI. Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. Nat Commun. 2020 01 14; 11(1):264. View on PubMed
28. Tran M, Braz JM, Hamel K, Kuhn J, Todd AJ, Basbaum AI. Ablation of spinal cord estrogen receptor α-expressing interneurons reduces chemically induced modalities of pain and itch. J Comp Neurol. 2020 07; 528(10):1629-1643. View on PubMed
29. Wercberger R, Basbaum AI. Spinal cord projection neurons: a superficial, and also deep, analysis. Curr Opin Physiol. 2019 Oct; 11:109-115. View on PubMed
30. Juarez-Salinas DL, Braz JM, Etlin A, Gee S, Sohal V, Basbaum AI. GABAergic cell transplants in the anterior cingulate cortex reduce neuropathic pain aversiveness. Brain. 2019 09 01; 142(9):2655-2669. View on PubMed
31. Wang X, Yvone GM, Cilluffo M, Kim AS, Basbaum AI, Phelps PE. Mispositioned Neurokinin-1 Receptor-Expressing Neurons Underlie Heat Hyperalgesia in Disabled-1 Mutant Mice. eNeuro. 2019 May/Jun; 6(3). View on PubMed
32. Meda KS, Patel T, Braz JM, Malik R, Turner ML, Seifikar H, Basbaum AI, Sohal VS. Microcircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion. Neuron. 2019 06 05; 102(5):944-959.e3. View on PubMed
33. Dickie AC, Bell AM, Iwagaki N, Polgár E, Gutierrez-Mecinas M, Kelly R, Lyon H, Turnbull K, West SJ, Etlin A, Braz J, Watanabe M, Bennett DLH, Basbaum AI, Riddell JS, Todd AJ. Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn. Pain. 2019 Feb; 160(2):442-462. View on PubMed
34. Dembo T, Braz JM, Hamel KA, Kuhn JA, Basbaum AI. Primary Afferent-Derived BDNF Contributes Minimally to the Processing of Pain and Itch. eNeuro. 2018 Nov-Dec; 5(6). View on PubMed
35. Juarez-Salinas DL, Braz JM, Hamel KA, Basbaum AI. Pain relief by supraspinal gabapentin requires descending noradrenergic inhibitory controls. Pain Rep. 2018 Jul-Aug; 3(4):e659. View on PubMed
36. Price TJ, Basbaum AI, Bresnahan J, Chambers JF, De Koninck Y, Edwards RR, Ji RR, Katz J, Kavelaars A, Levine JD, Porter L, Schechter N, Sluka KA, Terman GW, Wager TD, Yaksh TL, Dworkin RH. Transition to chronic pain: opportunities for novel therapeutics. Nat Rev Neurosci. 2018 07; 19(7):383-384. View on PubMed
37. Salvatierra J, Castro J, Erickson A, Li Q, Braz J, Gilchrist J, Grundy L, Rychkov GY, Deiteren A, Rais R, King GF, Slusher BS, Basbaum A, Pasricha PJ, Brierley SM, Bosmans F. NaV1.1 inhibition can reduce visceral hypersensitivity. JCI Insight. 2018 06 07; 3(11). View on PubMed
38. Wang D, Tawfik VL, Corder G, Low SA, François A, Basbaum AI, Scherrer G. Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits. Neuron. 2018 04 04; 98(1):90-108.e5. View on PubMed
39. Llewellyn-Smith IJ, Basbaum AI, Bráz JM. Long-term, dynamic synaptic reorganization after GABAergic precursor cell transplantation into adult mouse spinal cord. J Comp Neurol. 2018 Feb 15; 526(3):480-495. View on PubMed
40. Basbaum A. Chemogenetic management of neuropathic pain. Brain. 2017 10 01; 140(10):2522-2525. View on PubMed
41. Tran M, Kuhn JA, Bráz JM, Basbaum AI. Neuronal aromatase expression in pain processing regions of the medullary and spinal cord dorsal horn. J Comp Neurol. 2017 Nov 01; 525(16):3414-3428. View on PubMed
42. Zhang C, Medzihradszky KF, Sánchez EE, Basbaum AI, Julius D. Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):E2524-E2532. View on PubMed
43. Cevikbas F, Braz JM, Wang X, Solorzano C, Sulk M, Buhl T, Steinhoff M, Basbaum AI. Synergistic antipruritic effects of gamma aminobutyric acid A and B agonists in a mouse model of atopic dermatitis. J Allergy Clin Immunol. 2017 Aug; 140(2):454-464.e2. View on PubMed
44. Braz JM, Etlin A, Juarez-Salinas D, Llewellyn-Smith IJ, Basbaum AI. Rebuilding CNS inhibitory circuits to control chronic neuropathic pain and itch. Prog Brain Res. 2017; 231:87-105. View on PubMed
45. Etlin A, Bráz JM, Kuhn JA, Wang X, Hamel KA, Llewellyn-Smith IJ, Basbaum AI. Functional Synaptic Integration of Forebrain GABAergic Precursors into the Adult Spinal Cord. J Neurosci. 2016 11 16; 36(46):11634-11645. View on PubMed
46. Frezel N, Sohet F, Daneman R, Basbaum AI, Braz JM. Peripheral and central neuronal ATF3 precedes CD4+ T-cell infiltration in EAE. Exp Neurol. 2016 09; 283(Pt A):224-34. View on PubMed
47. Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, Brierley SM, Basbaum AI, Bosmans F, King GF, Julius D. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. 2016 06 23; 534(7608):494-9. View on PubMed
48. Andrews NA, Latrémolière A, Basbaum AI, Mogil JS, Porreca F, Rice ASC, Woolf CJ, Currie GL, Dworkin RH, Eisenach JC, Evans S, Gewandter JS, Gover TD, Handwerker H, Huang W, Iyengar S, Jensen MP, Kennedy JD, Lee N, Levine J, Lidster K, Machin I, McDermott MP, McMahon SB, Price TJ, Ross SE, Scherrer G, Seal RP, Sena ES, Silva E, Stone L, Svensson CI, Turk DC, Whiteside G. Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations. Pain. 2016 Apr; 157(4):901-909. View on PubMed
49. Basbaum AI, Bráz JM. Cell transplants to treat the "disease" of neuropathic pain and itch. Pain. 2016 Feb; 157 Suppl 1:S42-S47. View on PubMed
50. Guan Z, Kuhn JA, Wang X, Colquitt B, Solorzano C, Vaman S, Guan AK, Evans-Reinsch Z, Braz J, Devor M, Abboud-Werner SL, Lanier LL, Lomvardas S, Basbaum AI. Injured sensory neuron-derived CSF1 induces microglial proliferation and DAP12-dependent pain. Nat Neurosci. 2016 Jan; 19(1):94-101. View on PubMed
51. Bonasera SJ, Schenk AK, Luxenberg EJ, Wang X, Basbaum A, Tecott LH. Mice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli. PLoS One. 2015; 10(12):e0142906. View on PubMed
52. Petitjean H, Pawlowski SA, Fraine SL, Sharif B, Hamad D, Fatima T, Berg J, Brown CM, Jan LY, Ribeiro-da-Silva A, Braz JM, Basbaum AI, Sharif-Naeini R. Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury. Cell Rep. 2015 Nov 10; 13(6):1246-1257. View on PubMed
53. Bráz JM, Wang F, Basbaum AI. Presynaptic Inputs to Any CNS Projection Neuron Identified by Dual Recombinant Virus Infection. PLoS One. 2015; 10(10):e0140681. View on PubMed
54. Brown JD, Saeed M, Do L, Braz J, Basbaum AI, Iadarola MJ, Wilson DM, Dillon WP. CT-guided injection of a TRPV1 agonist around dorsal root ganglia decreases pain transmission in swine. Sci Transl Med. 2015 Sep 16; 7(305):305ra145. View on PubMed
55. Villanueva L, Bouhassira D, Dickenson T, Basbaum A, Zimmermann M. In Memoriam Jean-Marie Besson 1938-2014. Eur J Pain. 2015 Aug; 19(7):871-6. View on PubMed
56. Bráz JM, Wang X, Guan Z, Rubenstein JL, Basbaum AI. Transplant-mediated enhancement of spinal cord GABAergic inhibition reverses paclitaxel-induced mechanical and heat hypersensitivity. Pain. 2015 Jun; 156(6):1084-1091. View on PubMed
57. Solorzano C, Villafuerte D, Meda K, Cevikbas F, Bráz J, Sharif-Naeini R, Juarez-Salinas D, Llewellyn-Smith IJ, Guan Z, Basbaum AI. Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns. J Neurosci. 2015 Jan 14; 35(2):648-57. View on PubMed
58. Braz JM, Juarez-Salinas D, Ross SE, Basbaum AI. Transplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch. J Clin Invest. 2014 Aug; 124(8):3612-6. View on PubMed
59. Braz J, Solorzano C, Wang X, Basbaum AI. Transmitting pain and itch messages: a contemporary view of the spinal cord circuits that generate gate control. Neuron. 2014 May 07; 82(3):522-36. View on PubMed
60. Southwell DG, Nicholas CR, Basbaum AI, Stryker MP, Kriegstein AR, Rubenstein JL, Alvarez-Buylla A. Interneurons from embryonic development to cell-based therapy. Science. 2014 Apr 11; 344(6180):1240622. View on PubMed
61. Bardoni R, Tawfik VL, Wang D, François A, Solorzano C, Shuster SA, Choudhury P, Betelli C, Cassidy C, Smith K, de Nooij JC, Mennicken F, O'Donnell D, Kieffer BL, Woodbury CJ, Basbaum AI, MacDermott AB, Scherrer G. Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn. Neuron. 2014 Mar 19; 81(6):1443. View on PubMed
62. Bardoni R, Tawfik VL, Wang D, François A, Solorzano C, Shuster SA, Choudhury P, Betelli C, Cassidy C, Smith K, de Nooij JC, Mennicken F, O'Donnell D, Kieffer BL, Woodbury CJ, Basbaum AI, MacDermott AB, Scherrer G. Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn. Neuron. 2014 Mar 19; 81(6):1312-1327. View on PubMed
63. Cevikbas F, Wang X, Akiyama T, Kempkes C, Savinko T, Antal A, Kukova G, Buhl T, Ikoma A, Buddenkotte J, Soumelis V, Feld M, Alenius H, Dillon SR, Carstens E, Homey B, Basbaum A, Steinhoff M. A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1. J Allergy Clin Immunol. 2014 Feb; 133(2):448-60. View on PubMed
64. Mandadi S, Hong P, Tran MA, Bráz JM, Colarusso P, Basbaum AI, Whelan PJ. Identification of multisegmental nociceptive afferents that modulate locomotor circuits in the neonatal mouse spinal cord. J Comp Neurol. 2013 Aug 15; 521(12):2870-87. View on PubMed
65. Huang F, Wang X, Ostertag EM, Nuwal T, Huang B, Jan YN, Basbaum AI, Jan LY. TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing. Nat Neurosci. 2013 Sep; 16(9):1284-90. View on PubMed
66. Wang X, Zhang J, Eberhart D, Urban R, Meda K, Solorzano C, Yamanaka H, Rice D, Basbaum AI. Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch. Neuron. 2013 Apr 24; 78(2):312-24. View on PubMed
67. Gibbs JL, Urban R, Basbaum AI. Paradoxical surrogate markers of dental injury-induced pain in the mouse. Pain. 2013 Aug; 154(8):1358-67. View on PubMed
68. Zhang J, Cavanaugh DJ, Nemenov MI, Basbaum AI. The modality-specific contribution of peptidergic and non-peptidergic nociceptors is manifest at the level of dorsal horn nociresponsive neurons. J Physiol. 2013 Feb 15; 591(4):1097-110. View on PubMed
69. Wang X, Babayan AH, Basbaum AI, Phelps PE. Loss of the Reelin-signaling pathway differentially disrupts heat, mechanical and chemical nociceptive processing. Neuroscience. 2012 Dec 13; 226:441-50. View on PubMed
70. Bráz JM, Sharif-Naeini R, Vogt D, Kriegstein A, Alvarez-Buylla A, Rubenstein JL, Basbaum AI. Forebrain GABAergic neuron precursors integrate into adult spinal cord and reduce injury-induced neuropathic pain. Neuron. 2012 May 24; 74(4):663-75. View on PubMed
71. Bohlen CJ, Chesler AT, Sharif-Naeini R, Medzihradszky KF, Zhou S, King D, Sánchez EE, Burlingame AL, Basbaum AI, Julius D. A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature. 2011 Nov 16; 479(7373):410-4. View on PubMed
72. Bráz JM, Ackerman L, Basbaum AI. Sciatic nerve transection triggers release and intercellular transfer of a genetically expressed macromolecular tracer in dorsal root ganglia. J Comp Neurol. 2011 Sep 01; 519(13):2648-57. View on PubMed
73. Cavanaugh DJ, Chesler AT, Bráz JM, Shah NM, Julius D, Basbaum AI. Restriction of transient receptor potential vanilloid-1 to the peptidergic subset of primary afferent neurons follows its developmental downregulation in nonpeptidergic neurons. J Neurosci. 2011 Jul 13; 31(28):10119-27. View on PubMed
74. Cavanaugh DJ, Chesler AT, Jackson AC, Sigal YM, Yamanaka H, Grant R, O'Donnell D, Nicoll RA, Shah NM, Julius D, Basbaum AI. Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J Neurosci. 2011 Mar 30; 31(13):5067-77. View on PubMed
75. Gibbs JL, Melnyk JL, Basbaum AI. Differential TRPV1 and TRPV2 channel expression in dental pulp. J Dent Res. 2011 Jun; 90(6):765-70. View on PubMed
76. Urban R, Scherrer G, Goulding EH, Tecott LH, Basbaum AI. Behavioral indices of ongoing pain are largely unchanged in male mice with tissue or nerve injury-induced mechanical hypersensitivity. Pain. 2011 May; 152(5):990-1000. View on PubMed
77. Sharif-Naeini R, Basbaum AI. Targeting pain where it resides ... In the brain. Sci Transl Med. 2011 Jan 12; 3(65):65ps1. View on PubMed
78. Mogil JS, Basbaum AI. Introducing the Biennial review of pain. Pain. 2011 Mar; 152(3 Suppl):S1. View on PubMed
79. Scherrer G, Low SA, Wang X, Zhang J, Yamanaka H, Urban R, Solorzano C, Harper B, Hnasko TS, Edwards RH, Basbaum AI. VGLUT2 expression in primary afferent neurons is essential for normal acute pain and injury-induced heat hypersensitivity. Proc Natl Acad Sci U S A. 2010 Dec 21; 107(51):22296-301. View on PubMed
80. Shields SD, Moore KD, Phelps PE, Basbaum AI. Olfactory ensheathing glia express aquaporin 1. J Comp Neurol. 2010 Nov 01; 518(21):4329-41. View on PubMed
81. Shields SD, Cavanaugh DJ, Lee H, Anderson DJ, Basbaum AI. Pain behavior in the formalin test persists after ablation of the great majority of C-fiber nociceptors. Pain. 2010 Nov; 151(2):422-429. View on PubMed
82. Bráz JM, Basbaum AI. Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli. Pain. 2010 Aug; 150(2):290-301. View on PubMed
83. Faktorovich EG, Basbaum AI. Effect of topical 0.5% morphine on postoperative pain after photorefractive keratectomy. J Refract Surg. 2010 Dec; 26(12):934-41. View on PubMed
84. Bates EA, Nikai T, Brennan KC, Fu YH, Charles AC, Basbaum AI, Ptácek LJ, Ahn AH. Sumatriptan alleviates nitroglycerin-induced mechanical and thermal allodynia in mice. Cephalalgia. 2010 Feb; 30(2):170-8. View on PubMed
85. Seal RP, Wang X, Guan Y, Raja SN, Woodbury CJ, Basbaum AI, Edwards RH. Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors. Nature. 2009 Dec 03; 462(7273):651-5. View on PubMed
86. Basbaum AI, Bautista DM, Scherrer G, Julius D. Cellular and molecular mechanisms of pain. Cell. 2009 Oct 16; 139(2):267-84. View on PubMed
87. Bráz JM, Basbaum AI. Triggering genetically-expressed transneuronal tracers by peripheral axotomy reveals convergent and segregated sensory neuron-spinal cord connectivity. Neuroscience. 2009 Nov 10; 163(4):1220-32. View on PubMed
88. Imamachi N, Park GH, Lee H, Anderson DJ, Simon MI, Basbaum AI, Han SK. TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):11330-5. View on PubMed
89. Scherrer G, Imamachi N, Cao YQ, Contet C, Mennicken F, O'Donnell D, Kieffer BL, Basbaum AI. Dissociation of the opioid receptor mechanisms that control mechanical and heat pain. Cell. 2009 Jun 12; 137(6):1148-59. View on PubMed
90. Cavanaugh DJ, Lee H, Lo L, Shields SD, Zylka MJ, Basbaum AI, Anderson DJ. Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. Proc Natl Acad Sci U S A. 2009 Jun 02; 106(22):9075-80. View on PubMed
91. Braz JM, Enquist LW, Basbaum AI. Inputs to serotonergic neurons revealed by conditional viral transneuronal tracing. J Comp Neurol. 2009 May 10; 514(2):145-60. View on PubMed
92. Wang X, Ratnam J, Zou B, England PM, Basbaum AI. TrkB signaling is required for both the induction and maintenance of tissue and nerve injury-induced persistent pain. J Neurosci. 2009 Apr 29; 29(17):5508-15. View on PubMed
93. Basbaum AI. Change is coming! Pain. 2009 Jan; 141(1-2):1. View on PubMed
94. Ossovskaya VS, Dolganov G, Basbaum AI. Loss of function genetic screens reveal MTGR1 as an intracellular repressor of beta1 integrin-dependent neurite outgrowth. J Neurosci Methods. 2009 Mar 15; 177(2):322-33. View on PubMed
95. Nikai T, Basbaum AI, Ahn AH. Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan. Pain. 2008 Oct 31; 139(3):533-540. View on PubMed
96. Neumann S, Braz JM, Skinner K, Llewellyn-Smith IJ, Basbaum AI. Innocuous, not noxious, input activates PKCgamma interneurons of the spinal dorsal horn via myelinated afferent fibers. J Neurosci. 2008 Aug 06; 28(32):7936-44. View on PubMed
97. Braz JM, Basbaum AI. Genetically expressed transneuronal tracer reveals direct and indirect serotonergic descending control circuits. J Comp Neurol. 2008 Apr 20; 507(6):1990-2003. View on PubMed
98. Akopians AL, Babayan AH, Beffert U, Herz J, Basbaum AI, Phelps PE. Contribution of the Reelin signaling pathways to nociceptive processing. Eur J Neurosci. 2008 Feb; 27(3):523-37. View on PubMed
99. Lewinter RD, Scherrer G, Basbaum AI. Dense transient receptor potential cation channel, vanilloid family, type 2 (TRPV2) immunoreactivity defines a subset of motoneurons in the dorsal lateral nucleus of the spinal cord, the nucleus ambiguus and the trigeminal motor nucleus in rat. Neuroscience. 2008 Jan 02; 151(1):164-73. View on PubMed
100. Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, Imamachi N, Andrè E, Patacchini R, Cottrell GS, Gatti R, Basbaum AI, Bunnett NW, Julius D, Geppetti P. 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A. 2007 Aug 14; 104(33):13519-24. View on PubMed
101. Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL, Jordt SE, Julius D. The menthol receptor TRPM8 is the principal detector of environmental cold. Nature. 2007 Jul 12; 448(7150):204-8. View on PubMed
102. Shields SD, Mazario J, Skinner K, Basbaum AI. Anatomical and functional analysis of aquaporin 1, a water channel in primary afferent neurons. Pain. 2007 Sep; 131(1-2):8-20. View on PubMed
103. Mazarío J, Basbaum AI. Contribution of substance P and neurokinin A to the differential injury-induced thermal and mechanical responsiveness of lamina I and V neurons. J Neurosci. 2007 Jan 24; 27(4):762-70. View on PubMed
104. Siemens J, Zhou S, Piskorowski R, Nikai T, Lumpkin EA, Basbaum AI, King D, Julius D. Spider toxins activate the capsaicin receptor to produce inflammatory pain. Nature. 2006 Nov 09; 444(7116):208-12. View on PubMed
105. Eckert WA, Julius D, Basbaum AI. Differential contribution of TRPV1 to thermal responses and tissue injury-induced sensitization of dorsal horn neurons in laminae I and V in the mouse. Pain. 2006 Dec 15; 126(1-3):184-97. View on PubMed
106. Basbaum AI. Reviews: topical, systematic and once again, comprehensive. Pain. 2006 Oct; 124(3):237. View on PubMed
107. Ahn AH, Basbaum AI. Tissue injury regulates serotonin 1D receptor expression: implications for the control of migraine and inflammatory pain. J Neurosci. 2006 Aug 09; 26(32):8332-8. View on PubMed
108. Scherrer G, Tryoen-Tóth P, Filliol D, Matifas A, Laustriat D, Cao YQ, Basbaum AI, Dierich A, Vonesh JL, Gavériaux-Ruff C, Kieffer BL. Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo. Proc Natl Acad Sci U S A. 2006 Jun 20; 103(25):9691-6. View on PubMed
109. Basbaum AI, Julius D. Toward better pain control. Sci Am. 2006 Jun; 294(6):60-7. View on PubMed
110. Woods AS, Kaminski R, Oz M, Wang Y, Hauser K, Goody R, Wang HY, Jackson SN, Zeitz P, Zeitz KP, Zolkowska D, Schepers R, Nold M, Danielson J, Gräslund A, Vukojevic V, Bakalkin G, Basbaum A, Shippenberg T. Decoy peptides that bind dynorphin noncovalently prevent NMDA receptor-mediated neurotoxicity. J Proteome Res. 2006 Apr; 5(4):1017-23. View on PubMed
111. Villeda SA, Akopians AL, Babayan AH, Basbaum AI, Phelps PE. Absence of Reelin results in altered nociception and aberrant neuronal positioning in the dorsal spinal cord. Neuroscience. 2006; 139(4):1385-96. View on PubMed
112. Bautista DM, Jordt SE, Nikai T, Tsuruda PR, Read AJ, Poblete J, Yamoah EN, Basbaum AI, Julius D. TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell. 2006 Mar 24; 124(6):1269-82. View on PubMed
113. Neumann S, Skinner K, Basbaum AI. Sustaining intrinsic growth capacity of adult neurons promotes spinal cord regeneration. Proc Natl Acad Sci U S A. 2005 Nov 15; 102(46):16848-52. View on PubMed
114. Braz JM, Nassar MA, Wood JN, Basbaum AI. Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor. Neuron. 2005 Sep 15; 47(6):787-93. View on PubMed
115. Julius D, Basbaum AI. A neuropeptide courier for delta-opioid receptors? Cell. 2005 Aug 26; 122(4):496-8. View on PubMed
116. Högestätt ED, Jönsson BA, Ermund A, Andersson DA, Björk H, Alexander JP, Cravatt BF, Basbaum AI, Zygmunt PM. Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system. J Biol Chem. 2005 Sep 09; 280(36):31405-12. View on PubMed
117. Ahn AH, Basbaum AI. Where do triptans act in the treatment of migraine? Pain. 2005 May; 115(1-2):1-4. View on PubMed
118. Basbaum AI. A new way to lose your nerve. Sci Aging Knowledge Environ. 2004 Apr 14; 2004(15):pe15. View on PubMed
119. Sanderson Nydahl K, Skinner K, Julius D, Basbaum AI. Co-localization of endomorphin-2 and substance P in primary afferent nociceptors and effects of injury: a light and electron microscopic study in the rat. Eur J Neurosci. 2004 Apr; 19(7):1789-99. View on PubMed
120. Lewinter RD, Skinner K, Julius D, Basbaum AI. Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat. J Comp Neurol. 2004 Mar 15; 470(4):400-8. View on PubMed
121. Martin WJ, Cao Y, Basbaum AI. Characterization of wide dynamic range neurons in the deep dorsal horn of the spinal cord in preprotachykinin-a null mice in vivo. J Neurophysiol. 2004 May; 91(5):1945-54. View on PubMed
122. Zeitz KP, Giese KP, Silva AJ, Basbaum AI. The contribution of autophosphorylated alpha-calcium-calmodulin kinase II to injury-induced persistent pain. Neuroscience. 2004; 128(4):889-98. View on PubMed
123. Trafton JA, Basbaum AI. [d-Ala2,N-MePhe4,Gly-ol5]enkephalin-induced internalization of the micro opioid receptor in the spinal cord of morphine tolerant rats. Neuroscience. 2004; 125(3):541-3. View on PubMed
124. Potrebic S, Ahn AH, Skinner K, Fields HL, Basbaum AI. Peptidergic nociceptors of both trigeminal and dorsal root ganglia express serotonin 1D receptors: implications for the selective antimigraine action of triptans. J Neurosci. 2003 Nov 26; 23(34):10988-97. View on PubMed
125. Shields SD, Eckert WA, Basbaum AI. Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis. J Pain. 2003 Oct; 4(8):465-70. View on PubMed
126. Taylor BK, Basbaum AI. Systemic morphine-induced release of serotonin in the rostroventral medulla is not mimicked by morphine microinjection into the periaqueductal gray. J Neurochem. 2003 Sep; 86(5):1129-41. View on PubMed
127. Bhatia M, Slavin J, Cao Y, Basbaum AI, Neoptolemos JP. Preprotachykinin-A gene deletion protects mice against acute pancreatitis and associated lung injury. Am J Physiol Gastrointest Liver Physiol. 2003 May; 284(5):G830-6. View on PubMed
128. Malmberg AB, Gilbert H, McCabe RT, Basbaum AI. Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T. Pain. 2003 Jan; 101(1-2):109-16. View on PubMed
129. Mitrovic I, Margeta-Mitrovic M, Bader S, Stoffel M, Jan LY, Basbaum AI. Contribution of GIRK2-mediated postsynaptic signaling to opiate and alpha 2-adrenergic analgesia and analgesic sex differences. Proc Natl Acad Sci U S A. 2003 Jan 07; 100(1):271-6. View on PubMed
130. Telgkamp P, Cao YQ, Basbaum AI, Ramirez JM. Long-term deprivation of substance P in PPT-A mutant mice alters the anoxic response of the isolated respiratory network. J Neurophysiol. 2002 Jul; 88(1):206-13. View on PubMed
131. Neumann S, Bradke F, Tessier-Lavigne M, Basbaum AI. Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation. Neuron. 2002 Jun 13; 34(6):885-93. View on PubMed
132. Abbadie C, Lombard MC, Besson JM, Trafton JA, Basbaum AI. Mu and delta opioid receptor-like immunoreactivity in the cervical spinal cord of the rat after dorsal rhizotomy or neonatal capsaicin: an analysis of pre- and postsynaptic receptor distributions. Brain Res. 2002 Mar 15; 930(1-2):150-62. View on PubMed
133. Zeitz KP, Guy N, Malmberg AB, Dirajlal S, Martin WJ, Sun L, Bonhaus DW, Stucky CL, Julius D, Basbaum AI. The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. J Neurosci. 2002 Feb 01; 22(3):1010-9. View on PubMed
134. Zeitz KP, Malmberg AB, Gilbert H, Basbaum AI. Reduced development of tolerance to the analgesic effects of morphine and clonidine in PKC gamma mutant mice. Pain. 2001 Dec; 94(3):245-253. View on PubMed
135. Julius D, Basbaum AI. Molecular mechanisms of nociception. Nature. 2001 Sep 13; 413(6852):203-10. View on PubMed
136. Martin WJ, Malmberg AB, Basbaum AI. PKCgamma contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain. J Neurosci. 2001 Jul 15; 21(14):5321-7. View on PubMed
137. Vergnolle N, Bunnett NW, Sharkey KA, Brussee V, Compton SJ, Grady EF, Cirino G, Gerard N, Basbaum AI, Andrade-Gordon P, Hollenberg MD, Wallace JL. Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway. Nat Med. 2001 Jul; 7(7):821-6. View on PubMed
138. Chuang HH, Prescott ED, Kong H, Shields S, Jordt SE, Basbaum AI, Chao MV, Julius D. Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. Nature. 2001 Jun 21; 411(6840):957-62. View on PubMed
139. Trafton JA, Abbadie C, Basbaum AI. Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat. J Neurosci. 2001 May 15; 21(10):3656-64. View on PubMed
140. Malmberg AB, Hedley LR, Jasper JR, Hunter JC, Basbaum AI. Contribution of alpha(2) receptor subtypes to nerve injury-induced pain and its regulation by dexmedetomidine. Br J Pharmacol. 2001 Apr; 132(8):1827-36. View on PubMed
141. Taylor BK, Roderick RE, St Lezin E, Basbaum AI. Hypoalgesia and hyperalgesia with inherited hypertension in the rat. Am J Physiol Regul Integr Comp Physiol. 2001 Feb; 280(2):R345-54. View on PubMed
142. Riley RC, Trafton JA, Chi SI, Basbaum AI. Presynaptic regulation of spinal cord tachykinin signaling via GABA(B) but not GABA(A) receptor activation. Neuroscience. 2001; 103(3):725-37. View on PubMed
143. Trafton JA, Abbadie C, Marek K, Basbaum AI. Postsynaptic signaling via the [mu]-opioid receptor: responses of dorsal horn neurons to exogenous opioids and noxious stimulation. J Neurosci. 2000 Dec 01; 20(23):8578-84. View on PubMed
144. Taylor BK, Roderick RE, Basbaum AI. Brainstem noradrenergic control of nociception is abnormal in the spontaneously hypertensive rat. Neurosci Lett. 2000 Sep 22; 291(3):139-42. View on PubMed
145. Trafton JA, Basbaum AI. The contribution of spinal cord neurokinin-1 receptor signaling to pain. J Pain. 2000 Sep; 1(3 Suppl):57-65. View on PubMed
146. Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen-Zeitz KR, Koltzenburg M, Basbaum AI, Julius D. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science. 2000 Apr 14; 288(5464):306-13. View on PubMed
147. Taylor BK, Peterson MA, Roderick RE, Tate J, Green PG, Levine JO, Basbaum AI. Opioid inhibition of formalin-induced changes in plasma extravasation and local blood flow in rats. Pain. 2000 Feb; 84(2-3):263-70. View on PubMed
148. Mitchell JM, Basbaum AI, Fields HL. A locus and mechanism of action for associative morphine tolerance. Nat Neurosci. 2000 Jan; 3(1):47-53. View on PubMed
149. Taylor BK, Basbaum AI. Early antinociception delays edema but does not reduce the magnitude of persistent pain in the formalin test. J Pain. 2000; 1(3):218-28. View on PubMed
150. Mogil JS, Yu L, Basbaum AI. Pain genes?: natural variation and transgenic mutants. Annu Rev Neurosci. 2000; 23:777-811. View on PubMed
151. Trafton JA, Abbadie C, Marchand S, Mantyh PW, Basbaum AI. Spinal opioid analgesia: how critical is the regulation of substance P signaling? J Neurosci. 1999 Nov 01; 19(21):9642-53. View on PubMed
152. Stryker MP, Basbaum A, DeFranco T, Herskowitz I, Yamamoto K. Hospital merger leaves clinical science intact. Nature. 1999 Oct 28; 401(6756):842. View on PubMed
153. Liu H, Cao Y, Basbaum AI, Mazarati AM, Sankar R, Wasterlain CG. Resistance to excitotoxin-induced seizures and neuronal death in mice lacking the preprotachykinin A gene. Proc Natl Acad Sci U S A. 1999 Oct 12; 96(21):12096-101. View on PubMed
154. Honor P, Menning PM, Rogers SD, Nichols ML, Basbaum AI, Besson JM, Mantyh PW. Spinal substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states. J Neurosci. 1999 Sep 01; 19(17):7670-8. View on PubMed
155. Petersen-Zeitz KR, Basbaum AI. Second messengers, the substantia gelatinosa and injury-induced persistent pain. Pain. 1999 Aug; Suppl 6:S5-S12. View on PubMed
156. Martin WJ, Loo CM, Basbaum AI. Spinal cannabinoids are anti-allodynic in rats with persistent inflammation. Pain. 1999 Aug; 82(2):199-205. View on PubMed
157. Basbaum AI. Distinct neurochemical features of acute and persistent pain. Proc Natl Acad Sci U S A. 1999 Jul 06; 96(14):7739-43. View on PubMed
158. Basbaum AI, Woolf CJ. Pain. Curr Biol. 1999 Jun 17; 9(12):R429-31. View on PubMed
159. Margeta-Mitrovic M, Mitrovic I, Riley RC, Jan LY, Basbaum AI. Immunohistochemical localization of GABA(B) receptors in the rat central nervous system. J Comp Neurol. 1999 Mar 15; 405(3):299-321. View on PubMed
160. Martin WJ, Gupta NK, Loo CM, Rohde DS, Basbaum AI. Differential effects of neurotoxic destruction of descending noradrenergic pathways on acute and persistent nociceptive processing. Pain. 1999 Mar; 80(1-2):57-65. View on PubMed
161. Abbadie C, Skinner K, Mitrovic I, Basbaum AI. Neurons in the dorsal column white matter of the spinal cord: complex neuropil in an unexpected location. Proc Natl Acad Sci U S A. 1999 Jan 05; 96(1):260-5. View on PubMed
162. Martin WJ, Liu H, Wang H, Malmberg AB, Basbaum AI. Inflammation-induced up-regulation of protein kinase Cgamma immunoreactivity in rat spinal cord correlates with enhanced nociceptive processing. Neuroscience. 1999; 88(4):1267-74. View on PubMed
163. Basbaum AI. Spinal mechanisms of acute and persistent pain. Reg Anesth Pain Med. 1999 Jan-Feb; 24(1):59-67. View on PubMed
164. Abbadie C, Basbaum AI. The contribution of capsaicin-sensitive afferents to the dorsal root ganglion sprouting of sympathetic axons after peripheral nerve injury in the rat. Neurosci Lett. 1998 Sep 11; 253(3):143-6. View on PubMed
165. Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, Julius D. The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron. 1998 Sep; 21(3):531-43. View on PubMed
166. Martin WJ, Malmberg AB, Basbaum AI. Pain: nocistatin spells relief. Curr Biol. 1998 Jul 16; 8(15):R525-7. View on PubMed
167. Bhatnagar S, Dallman MF, Roderick RE, Basbaum AI, Taylor BK. The effects of prior chronic stress on cardiovascular responses to acute restraint and formalin injection. Brain Res. 1998 Jun 29; 797(2):313-20. View on PubMed
168. Rohde DS, Basbaum AI. Activation of coeruleospinal noradrenergic inhibitory controls during withdrawal from morphine in the rat. J Neurosci. 1998 Jun 01; 18(11):4393-402. View on PubMed
169. Malmberg AB, Basbaum AI. Partial sciatic nerve injury in the mouse as a model of neuropathic pain: behavioral and neuroanatomical correlates. Pain. 1998 May; 76(1-2):215-22. View on PubMed
170. Taylor BK, Akana SF, Peterson MA, Dallman MF, Basbaum AI. Pituitary-adrenocortical responses to persistent noxious stimuli in the awake rat: endogenous corticosterone does not reduce nociception in the formalin test. Endocrinology. 1998 May; 139(5):2407-13. View on PubMed
171. Cao YQ, Mantyh PW, Carlson EJ, Gillespie AM, Epstein CJ, Basbaum AI. Primary afferent tachykinins are required to experience moderate to intense pain. Nature. 1998 Mar 26; 392(6674):390-4. View on PubMed
172. Hammond DL, Wang H, Nakashima N, Basbaum AI. Differential effects of intrathecally administered delta and mu opioid receptor agonists on formalin-evoked nociception and on the expression of Fos-like immunoreactivity in the spinal cord of the rat. J Pharmacol Exp Ther. 1998 Jan; 284(1):378-87. View on PubMed
173. Abbadie C, Trafton J, Liu H, Mantyh PW, Basbaum AI. Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation. J Neurosci. 1997 Oct 15; 17(20):8049-60. View on PubMed
174. Malmberg AB, Chen C, Tonegawa S, Basbaum AI. Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma. Science. 1997 Oct 10; 278(5336):279-83. View on PubMed
175. Malmberg AB, Brandon EP, Idzerda RL, Liu H, McKnight GS, Basbaum AI. Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of cAMP-dependent protein kinase. J Neurosci. 1997 Oct 01; 17(19):7462-70. View on PubMed
176. Skinner K, Basbaum AI, Fields HL. Cholecystokinin and enkephalin in brain stem pain modulating circuits. Neuroreport. 1997 Sep 29; 8(14):2995-8. View on PubMed
177. Rohde DS, McKay WR, Chang DS, Abbadie C, Basbaum AI. The contribution of supraspinal, peripheral and intrinsic spinal circuits to the pattern and magnitude of Fos-like immunoreactivity in the lumbar spinal cord of the rat withdrawing from morphine. Neuroscience. 1997 Sep; 80(2):599-612. View on PubMed
178. Rohde DS, Detweiler DJ, Basbaum AI. Formalin-evoked Fos expression in spinal cord is enhanced in morphine-tolerant rats. Brain Res. 1997 Aug 22; 766(1-2):93-100. View on PubMed
179. Allen BJ, Rogers SD, Ghilardi JR, Menning PM, Kuskowski MA, Basbaum AI, Simone DA, Mantyh PW. Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo. J Neurosci. 1997 Aug 01; 17(15):5921-7. View on PubMed
180. Jasmin L, Burkey AR, Card JP, Basbaum AI. Transneuronal labeling of a nociceptive pathway, the spino-(trigemino-)parabrachio-amygdaloid, in the rat. J Neurosci. 1997 May 15; 17(10):3751-65. View on PubMed
181. Peterson MA, Basbaum AI, Abbadie C, Rohde DS, McKay WR, Taylor BK. The differential contribution of capsaicin-sensitive afferents to behavioral and cardiovascular measures of brief and persistent nociception and to Fos expression in the formalin test. Brain Res. 1997 Apr 25; 755(1):9-16. View on PubMed
182. Liu H, Mantyh PW, Basbaum AI. NMDA-receptor regulation of substance P release from primary afferent nociceptors. Nature. 1997 Apr 17; 386(6626):721-4. View on PubMed
183. Llewellyn-Smith IJ, Martin CL, Minson JB, Pilowsky PM, Arnolda LF, Basbaum AI, Chalmers JP. Neurokinin-1 receptor-immunoreactive sympathetic preganglionic neurons: target specificity and ultrastructure. Neuroscience. 1997 Apr; 77(4):1137-49. View on PubMed
184. Skinner K, Fields HL, Basbaum AI, Mason P. GABA-immunoreactive boutons contact identified OFF and ON cells in the nucleus raphe magnus. J Comp Neurol. 1997 Feb 10; 378(2):196-204. View on PubMed
185. Taylor BK, Peterson MA, Basbaum AI. Early nociceptive events influence the temporal profile, but not the magnitude, of the tonic response to subcutaneous formalin: effects with remifentanil. J Pharmacol Exp Ther. 1997 Feb; 280(2):876-83. View on PubMed
186. Jasmin L, Carstens E, Basbaum AI. Interneurons presynaptic to rat tail-flick motoneurons as mapped by transneuronal transport of pseudorabies virus: few have long ascending collaterals. Neuroscience. 1997 Feb; 76(3):859-76. View on PubMed
187. Rohde DS, McKay WR, Abbadie C, Basbaum AI. Contribution of sacral spinal cord neurons to the autonomic and somatic consequences of withdrawal from morphine in the rat. Brain Res. 1997 Jan 16; 745(1-2):83-95. View on PubMed
188. Taylor BK, Peterson MA, Basbaum AI. Continuous intravenous infusion of naloxone does not change behavioral, cardiovascular, or inflammatory responses to subcutaneous formalin in the rat. Pain. 1997 Jan; 69(1-2):171-7. View on PubMed
189. Abbadie C, Taylor BK, Peterson MA, Basbaum AI. Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the rat spinal cord: studies with remifentanil and lidocaine. Pain. 1997 Jan; 69(1-2):101-10. View on PubMed
190. Rohde DS, Detweiler DJ, Basbaum AI. Spinal cord mechanisms of opioid tolerance and dependence: Fos-like immunoreactivity increases in subpopulations of spinal cord neurons during withdrawal [corrected]. Neuroscience. 1996 May; 72(1):233-42. View on PubMed
191. Gogas KR, Cho HJ, Botchkina GI, Levine JD, Basbaum AI. Inhibition of noxious stimulus-evoked pain behaviors and neuronal fos-like immunoreactivity in the spinal cord of the rat by supraspinal morphine. Pain. 1996 Apr; 65(1):9-15. View on PubMed
192. Gogas KR, Levine JD, Basbaum AI. Differential contribution of descending controls to the antinociceptive actions of kappa and mu opioids: an analysis of formalin-evoked C-fos expression. J Pharmacol Exp Ther. 1996 Feb; 276(2):801-9. View on PubMed
193. Abbadie C, Brown JL, Mantyh PW, Basbaum AI. Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain. Neuroscience. 1996 Jan; 70(1):201-9. View on PubMed
194. Taylor BK, Peterson MA, Basbaum AI. Exaggerated cardiovascular and behavioral nociceptive responses to subcutaneous formalin in the spontaneously hypertensive rat. Neurosci Lett. 1995 Dec 01; 201(1):9-12. View on PubMed
195. Taylor BK, Peterson MA, Basbaum AI. Persistent cardiovascular and behavioral nociceptive responses to subcutaneous formalin require peripheral nerve input. J Neurosci. 1995 Nov; 15(11):7575-84. View on PubMed
196. Detweiler DJ, Rohde DS, Basbaum AI. The development of opioid tolerance in the formalin test in the rat. Pain. 1995 Nov; 63(2):251-254. View on PubMed
197. Matos FF, Rollema H, Taiwo YO, Levine JD, Basbaum AI. Relationship between analgesia and extracellular morphine in brain and spinal cord in awake rats. Brain Res. 1995 Sep 25; 693(1-2):187-95. View on PubMed
198. Taylor BK, Basbaum AI. Neurochemical characterization of extracellular serotonin in the rostral ventromedial medulla and its modulation by noxious stimuli. J Neurochem. 1995 Aug; 65(2):578-89. View on PubMed
199. Mantyh PW, DeMaster E, Malhotra A, Ghilardi JR, Rogers SD, Mantyh CR, Liu H, Basbaum AI, Vigna SR, Maggio JE. Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation. Science. 1995 Jun 16; 268(5217):1629-32. View on PubMed
200. Brown JL, Liu H, Maggio JE, Vigna SR, Mantyh PW, Basbaum AI. Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis. J Comp Neurol. 1995 Jun 05; 356(3):327-44. View on PubMed
201. Basbaum AI. Insights into the development of opioid tolerance. Pain. 1995 Jun; 61(3):349-352. View on PubMed
202. Liu H, Llewellyn-Smith IJ, Basbaum AI. Co-injection of wheat germ agglutinin-HRP and choleragenoid-HRP into the sciatic nerve of the rat blocks transganglionic transport. J Histochem Cytochem. 1995 May; 43(5):489-95. View on PubMed
203. Mantyh PW, Allen CJ, Ghilardi JR, Rogers SD, Mantyh CR, Liu H, Basbaum AI, Vigna SR, Maggio JE. Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo. Proc Natl Acad Sci U S A. 1995 Mar 28; 92(7):2622-6. View on PubMed
204. Jasmin L, Wang H, Tarczy-Hornoch K, Levine JD, Basbaum AI. Differential effects of morphine on noxious stimulus-evoked fos-like immunoreactivity in subpopulations of spinoparabrachial neurons. J Neurosci. 1994 Dec; 14(12):7252-60. View on PubMed
205. Miao FJ, Jänig W, Dallman MF, Benowitz NL, Heller PH, Basbaum AI, Levine JD. Role of vagal afferents and spinal pathways modulating inhibition of bradykinin-induced plasma extravasation by intrathecal nicotine. J Neurophysiol. 1994 Sep; 72(3):1199-207. View on PubMed
206. Liu H, Wang H, Sheng M, Jan LY, Jan YN, Basbaum AI. Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn. Proc Natl Acad Sci U S A. 1994 Aug 30; 91(18):8383-7. View on PubMed
207. Morgan MM, Gogas KR, Basbaum AI. Diffuse noxious inhibitory controls reduce the expression of noxious stimulus-evoked Fos-like immunoreactivity in the superficial and deep laminae of the rat spinal cord. Pain. 1994 Mar; 56(3):347-352. View on PubMed
208. Liu H, Brown JL, Jasmin L, Maggio JE, Vigna SR, Mantyh PW, Basbaum AI. Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors. Proc Natl Acad Sci U S A. 1994 Feb 01; 91(3):1009-13. View on PubMed
209. Jasmin L, Tarczy-Hornoch K, Wang H, Levine JD, Basbaum AI. Transneuronal spread of the pseudorabies virus after injection into the central nucleus of the amygdala in the rat. Gene Ther. 1994; 1 Suppl 1:S74. View on PubMed
210. Jasmin L, Gogas KR, Ahlgren SC, Levine JD, Basbaum AI. Walking evokes a distinctive pattern of Fos-like immunoreactivity in the caudal brainstem and spinal cord of the rat. Neuroscience. 1994 Jan; 58(2):275-86. View on PubMed
211. Chi SI, Levine JD, Basbaum AI. Effects of injury discharge on the persistent expression of spinal cord fos-like immunoreactivity produced by sciatic nerve transection in the rat. Brain Res. 1993 Jul 23; 617(2):220-4. View on PubMed
212. Chi SI, Levine JD, Basbaum AI. Peripheral and central contributions to the persistent expression of spinal cord fos-like immunoreactivity produced by sciatic nerve transection in the rat. Brain Res. 1993 Jul 23; 617(2):225-37. View on PubMed
213. Levine JD, Fields HL, Basbaum AI. Peptides and the primary afferent nociceptor. J Neurosci. 1993 Jun; 13(6):2273-86. View on PubMed
214. Kwiat GC, Liu H, Williamson AM, Basbaum AI. GABAergic regulation of noradrenergic spinal projection neurons of the A5 cell group in the rat: an electron microscopic analysis. J Comp Neurol. 1993 Apr 22; 330(4):557-70. View on PubMed
215. Miao FJ, Dallman MF, Benowitz NL, Basbaum AI, Levine JD. Adrenal medullary modulation of the inhibition of bradykinin-induced plasma extravasation by intrathecal nicotine. J Pharmacol Exp Ther. 1993 Feb; 264(2):839-44. View on PubMed
216. Gogas KR, Levine JD, Basbaum AI. Mechanisms of opioid-mediated antinociception: correlation of Fos expression and behavior. NIDA Res Monogr. 1993; 125:134-60. View on PubMed
217. Miao FJ, Helms C, Benowitz NL, Basbaum AI, Heller PH, Levine JD. Chronically administered nicotine attenuates bradykinin-induced plasma extravasation and aggravates arthritis-induced joint injury in the rat. Neuroscience. 1992 Dec; 51(3):649-55. View on PubMed
218. Green PG, Basbaum AI, Levine JD. Sensory neuropeptide interactions in the production of plasma extravasation in the rat. Neuroscience. 1992 Oct; 50(3):745-9. View on PubMed
219. Miao FJ, Benowitz NL, Basbaum AI, Levine JD. Sympathoadrenal contribution to nicotinic and muscarinic modulation of bradykinin-induced plasma extravasation in the knee joint of the rat. J Pharmacol Exp Ther. 1992 Sep; 262(3):889-95. View on PubMed
220. Frothingham EP, Basbaum AI. Construction of a microdialysis probe with attached microinjection catheter. J Neurosci Methods. 1992 Jul; 43(2-3):181-8. View on PubMed
221. Sato M, Severinghaus JW, Basbaum AI. Medullary CO2 chemoreceptor neuron identification by c-fos immunocytochemistry. J Appl Physiol (1985). 1992 Jul; 73(1):96-100. View on PubMed
222. Matos FF, Rollema H, Basbaum AI. Simultaneous measurement of extracellular morphine and serotonin in brain tissue and CSF by microdialysis in awake rats. J Neurochem. 1992 May; 58(5):1773-81. View on PubMed
223. Liu H, Llewellyn-Smith IJ, Pilowsky P, Basbaum AI. Ultrastructural evidence for GABA-mediated disinhibitory circuits in the spinal cord of the cat. Neurosci Lett. 1992 Apr 13; 138(1):183-7. View on PubMed
224. Matos FF, Rollema H, Brown JL, Basbaum AI. Do opioids evoke the release of serotonin in the spinal cord? An in vivo microdialysis study of the regulation of extracellular serotonin in the rat. Pain. 1992 Mar; 48(3):439-447. View on PubMed
225. Hammond DL, Presley R, Gogas KR, Basbaum AI. Morphine or U-50,488 suppresses Fos protein-like immunoreactivity in the spinal cord and nucleus tractus solitarii evoked by a noxious visceral stimulus in the rat. J Comp Neurol. 1992 Jan 08; 315(2):244-53. View on PubMed
226. Basbaum AI. Opioid regulation of nociceptive and neuropathic pain. Clin Neuropharmacol. 1992; 15 Suppl 1 Pt A:372A. View on PubMed
227. Kwiat GC, Basbaum AI. The origin of brainstem noradrenergic and serotonergic projections to the spinal cord dorsal horn in the rat. Somatosens Mot Res. 1992; 9(2):157-73. View on PubMed
228. Basbaum AI, Gautron M, Jazat F, Mayes M, Guilbaud G. The spectrum of fiber loss in a model of neuropathic pain in the rat: an electron microscopic study. Pain. 1991 Dec; 47(3):359-367. View on PubMed
229. Basbaum AI, Levine JD. Opiate analgesia. How central is a peripheral target? N Engl J Med. 1991 Oct 17; 325(16):1168-9. View on PubMed
230. Lee A, Coderre TJ, Basbaum AI, Levine JD. Sympathetic neuron factors involved in bradykinin-induced plasma extravasation in the rat. Brain Res. 1991 Aug 23; 557(1-2):146-8. View on PubMed
231. Green PG, Basbaum AI, Helms C, Levine JD. Purinergic regulation of bradykinin-induced plasma extravasation and adjuvant-induced arthritis in the rat. Proc Natl Acad Sci U S A. 1991 May 15; 88(10):4162-5. View on PubMed
232. Basbaum AI, Levine JD. The contribution of the nervous system to inflammation and inflammatory disease. Can J Physiol Pharmacol. 1991 May; 69(5):647-51. View on PubMed
233. Coderre TJ, Basbaum AI, Helms C, Levine JD. High-dose epinephrine acts at alpha 2-adrenoceptors to suppress experimental arthritis. Brain Res. 1991 Mar 29; 544(2):325-8. View on PubMed
234. Cho HJ, Basbaum AI. GABAergic circuitry in the rostral ventral medulla of the rat and its relationship to descending antinociceptive controls. J Comp Neurol. 1991 Jan 08; 303(2):316-28. View on PubMed
235. Reichling DB, Basbaum AI. Collateralization of periaqueductal gray neurons to forebrain or diencephalon and to the medullary nucleus raphe magnus in the rat. Neuroscience. 1991; 42(1):183-200. View on PubMed
236. Coderre TJ, Chan AK, Helms C, Basbaum AI, Levine JD. Increasing sympathetic nerve terminal-dependent plasma extravasation correlates with decreased arthritic joint injury in rats. Neuroscience. 1991; 40(1):185-9. View on PubMed
237. Bjerknes L, Coderre TJ, Green PG, Basbaum AI, Levine JD. Neutrophils contribute to sympathetic nerve terminal-dependent plasma extravasation in the knee joint of the rat. Neuroscience. 1991; 43(2-3):679-85. View on PubMed
238. Gogas KR, Presley RW, Levine JD, Basbaum AI. The antinociceptive action of supraspinal opioids results from an increase in descending inhibitory control: correlation of nociceptive behavior and c-fos expression. Neuroscience. 1991; 42(3):617-28. View on PubMed
239. Reichling DB, Basbaum AI. Contribution of brainstem GABAergic circuitry to descending antinociceptive controls: I. GABA-immunoreactive projection neurons in the periaqueductal gray and nucleus raphe magnus. J Comp Neurol. 1990 Dec 08; 302(2):370-7. View on PubMed
240. Reichling DB, Basbaum AI. Contribution of brainstem GABAergic circuitry to descending antinociceptive controls: II. Electron microscopic immunocytochemical evidence of GABAergic control over the projection from the periaqueductal gray to the nucleus raphe magnus in the rat. J Comp Neurol. 1990 Dec 08; 302(2):378-93. View on PubMed
241. Levine JD, Coderre TJ, White DM, Finkbeiner WE, Basbaum AI. Denervation-induced inflammation in the rat. Neurosci Lett. 1990 Oct 30; 119(1):37-40. View on PubMed
242. Matos FF, Rollema H, Basbaum AI. Characterization of monoamine release in the lateral hypothalamus of awake, freely moving rats using in vivo microdialysis. Brain Res. 1990 Sep 24; 528(1):39-47. View on PubMed
243. Kwiat GC, Basbaum AI. Organization of tyrosine hydroxylase- and serotonin-immunoreactive brainstem neurons with axon collaterals to the periaqueductal gray and the spinal cord in the rat. Brain Res. 1990 Sep 24; 528(1):83-94. View on PubMed
244. Levine JD, Coderre TJ, Covinsky K, Basbaum AI. Neural influences on synovial mast cell density in rat. J Neurosci Res. 1990 Jul; 26(3):301-7. View on PubMed
245. White DM, Basbaum AI, Goetzl EJ, Levine JD. The 15-lipoxygenase product, 8R,15S-diHETE, stereospecifically sensitizes C-fiber mechanoheat nociceptors in hairy skin of rat. J Neurophysiol. 1990 May; 63(5):966-70. View on PubMed
246. Levine JD, Basbaum AI. Neurogenic mechanism for symmetrical arthritis. Lancet. 1990 Mar 31; 335(8692):795. View on PubMed
247. Kayser V, Basbaum AI, Guilbaud G. Deafferentation in the rat increases mechanical nociceptive threshold in the innervated limbs. Brain Res. 1990 Feb 05; 508(2):329-32. View on PubMed
248. Coderre TJ, Basbaum AI, Dallman MF, Helms C, Levine JD. Epinephrine exacerbates arthritis by an action at presynaptic B2-adrenoceptors. Neuroscience. 1990; 34(2):521-3. View on PubMed
249. Presley RW, Menétrey D, Levine JD, Basbaum AI. Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord. J Neurosci. 1990 Jan; 10(1):323-35. View on PubMed
250. Basbaum AI. A rapid and simple silver enhancement procedure for ultrastructural localization of the retrograde tracer WGAapoHRP-Au and its use in double-label studies with post-embedding immunocytochemistry. J Histochem Cytochem. 1989 Dec; 37(12):1811-5. View on PubMed
251. Menétrey D, Gannon A, Levine JD, Basbaum AI. Expression of c-fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular, and visceral stimulation. J Comp Neurol. 1989 Jul 08; 285(2):177-95. View on PubMed
252. Coderre TJ, Basbaum AI, Levine JD. Neural control of vascular permeability: interactions between primary afferents, mast cells, and sympathetic efferents. J Neurophysiol. 1989 Jul; 62(1):48-58. View on PubMed
253. Weil-Fugazza J, Godefroy F, Basbaum AI. Effect of deafferentation on the levels of uric acid in the spinal cord of the rat. Neurosci Lett. 1989 Apr 24; 99(1-2):181-6. View on PubMed
254. Taiwo YO, Basbaum AI, Perry F, Levine JD. Paradoxical analgesia produced by low doses of the opiate-antagonist naloxone is mediated by interaction at a site with characteristics of the delta opioid receptor. J Pharmacol Exp Ther. 1989 Apr; 249(1):97-100. View on PubMed
255. Cho HJ, Basbaum AI. Ultrastructural analysis of dynorphin B-immunoreactive cells and terminals in the superficial dorsal horn of the deafferented spinal cord of the rat. J Comp Neurol. 1989 Mar 08; 281(2):193-205. View on PubMed
256. Cho HJ, Basbaum AI. Arborization of single axons of the spinal dorsolateral funiculus to the contralateral superficial dorsal horn. Brain Res. 1989 Jan 16; 477(1-2):344-9. View on PubMed
257. Basbaum AI. Distribution of glycine receptor immunoreactivity in the spinal cord of the rat: cytochemical evidence for a differential glycinergic control of lamina I and V nociceptive neurons. J Comp Neurol. 1988 Dec 15; 278(3):330-6. View on PubMed
258. Martin HA, Basbaum AI, Goetzl EJ, Levine JD. Leukotriene B4 decreases the mechanical and thermal thresholds of C-fiber nociceptors in the hairy skin of the rat. J Neurophysiol. 1988 Aug; 60(2):438-45. View on PubMed
259. Levine JD, Coderre TJ, Helms C, Basbaum AI. Beta 2-adrenergic mechanisms in experimental arthritis. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4553-6. View on PubMed
260. Faden AI, Gannon A, Basbaum AI. Use of serotonin immunocytochemistry as a marker of injury severity after experimental spinal trauma in rats. Brain Res. 1988 May 31; 450(1-2):94-100. View on PubMed
261. Levine JD, Moskowitz MA, Basbaum AI. The effect of gold, an antirheumatic therapy, on substance P levels in rat peripheral nerve. Neurosci Lett. 1988 Apr 22; 87(1-2):200-2. View on PubMed
262. Lakos S, Basbaum AI. An ultrastructural study of the projections from the midbrain periaqueductal gray to spinally projecting, serotonin-immunoreactive neurons of the medullary nucleus raphe magnus in the rat. Brain Res. 1988 Mar 08; 443(1-2):383-8. View on PubMed
263. Cho HJ, Basbaum AI. Increased staining of immunoreactive dynorphin cell bodies in the deafferented spinal cord of the rat. Neurosci Lett. 1988 Jan 22; 84(2):125-30. View on PubMed
264. Basbaum AI. Anatomical introduction to analgesia: correlation of activity of neurons of the superficial dorsal horn with pain and analgesia. Acta Anaesthesiol Belg. 1988; 39(3 Suppl 2):45-6. View on PubMed
265. Reichling DB, Kwiat GC, Basbaum AI. Anatomy, physiology and pharmacology of the periaqueductal gray contribution to antinociceptive controls. Prog Brain Res. 1988; 77:31-46. View on PubMed
266. Basbaum AI, Zahs K, Lord B, Lakos S. The fiber caliber of 5-HT immunoreactive axons in the dorsolateral funiculus of the spinal cord of the rat and cat. Somatosens Res. 1988; 5(3):177-85. View on PubMed
267. Daval G, Vergé D, Basbaum AI, Bourgoin S, Hamon M. Autoradiographic evidence of serotonin1 binding sites on primary afferent fibres in the dorsal horn of the rat spinal cord. Neurosci Lett. 1987 Dec 16; 83(1-2):71-6. View on PubMed
268. Menetrey D, Basbaum AI. The distribution of substance P-, enkephalin- and dynorphin-immunoreactive neurons in the medulla of the rat and their contribution to bulbospinal pathways. Neuroscience. 1987 Oct; 23(1):173-87. View on PubMed
269. Basbaum AI, Godefroy F, Weil-Fugazza J. A new microdissection technique for regional biochemical analysis of the rat spinal cord: serotonin, norepinephrine, dopamine and uric acid. Brain Res. 1987 Sep 01; 419(1-2):229-38. View on PubMed
270. Levine JD, Goetzl EJ, Basbaum AI. Contribution of the nervous system to the pathophysiology of rheumatoid arthritis and other polyarthritides. Rheum Dis Clin North Am. 1987 Aug; 13(2):369-83. View on PubMed
271. Martin HA, Basbaum AI, Kwiat GC, Goetzl EJ, Levine JD. Leukotriene and prostaglandin sensitization of cutaneous high-threshold C- and A-delta mechanonociceptors in the hairy skin of rat hindlimbs. Neuroscience. 1987 Aug; 22(2):651-9. View on PubMed
272. Basbaum AI, Menetrey D. Wheat germ agglutinin-apoHRP gold: a new retrograde tracer for light- and electron-microscopic single- and double-label studies. J Comp Neurol. 1987 Jul 08; 261(2):306-18. View on PubMed
273. Mochly-Rosen D, Basbaum AI, Koshland DE. Distinct cellular and regional localization of immunoreactive protein kinase C in rat brain. Proc Natl Acad Sci U S A. 1987 Jul; 84(13):4660-4. View on PubMed
274. Menétrey D, Basbaum AI. Spinal and trigeminal projections to the nucleus of the solitary tract: a possible substrate for somatovisceral and viscerovisceral reflex activation. J Comp Neurol. 1987 Jan 15; 255(3):439-50. View on PubMed
275. Basbaum AI. Cytochemical studies of the neural circuitry underlying pain and pain control. Acta Neurochir Suppl (Wien). 1987; 38:5-15. View on PubMed
276. Doble A, Malgouris C, Daniel M, Daniel N, Imbault F, Basbaum A, Uzan A, Guérémy C, Le Fur G. Labelling of peripheral-type benzodiazepine binding sites in human brain with [3H]PK 11195: anatomical and subcellular distribution. Brain Res Bull. 1987 Jan; 18(1):49-61. View on PubMed
277. Levine JD, Fye K, Heller P, Basbaum AI, Whiting-O'Keefe Q. Clinical response to regional intravenous guanethidine in patients with rheumatoid arthritis. J Rheumatol. 1986 Dec; 13(6):1040-3. View on PubMed
278. Levine JD, Dardick SJ, Roizen MF, Helms C, Basbaum AI. Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis. J Neurosci. 1986 Dec; 6(12):3423-9. View on PubMed
279. Basbaum AI, Ralston DD, Ralston HJ. Bulbospinal projections in the primate: a light and electron microscopic study of a pain modulating system. J Comp Neurol. 1986 Aug 15; 250(3):311-23. View on PubMed
280. Lakos S, Basbaum AI. Benzidine dihydrochloride as a chromogen for single- and double-label light and electron microscopic immunocytochemical studies. J Histochem Cytochem. 1986 Aug; 34(8):1047-56. View on PubMed
281. Dardick SJ, Basbaum AI, Levine JD. The contribution of pain to disability in experimentally induced arthritis. Arthritis Rheum. 1986 Aug; 29(8):1017-22. View on PubMed
282. Levine JD, Goldstine J, Mayes M, Moskowitz MA, Basbaum AI. The neurotoxic effect of gold sodium thiomalate on the peripheral nerves of the rat. Insights into the antiinflammatory actions of gold therapy. Arthritis Rheum. 1986 Jul; 29(7):897-901. View on PubMed
283. Basbaum AI, Cruz L, Weber E. Immunoreactive dynorphin B in sacral primary afferent fibers of the cat. J Neurosci. 1986 Jan; 6(1):127-33. View on PubMed
284. Basbaum AI, Glazer EJ, Oertel W. Immunoreactive glutamic acid decarboxylase in the trigeminal nucleus caudalis of the cat: a light- and electron-microscopic analysis. Somatosens Res. 1986; 4(1):77-94. View on PubMed
285. Brown RO, Gusman D, Basbaum AI, Mayeri E. Identification of Aplysia neurons containing immunoreactive FMRFamide. Neuropeptides. 1985 Dec; 6(6):517-26. View on PubMed
286. Cruz L, Basbaum AI. Multiple opioid peptides and the modulation of pain: immunohistochemical analysis of dynorphin and enkephalin in the trigeminal nucleus caudalis and spinal cord of the cat. J Comp Neurol. 1985 Oct 22; 240(4):331-48. View on PubMed
287. Levine JD, Moskowitz MA, Basbaum AI. The contribution of neurogenic inflammation in experimental arthritis. J Immunol. 1985 Aug; 135(2 Suppl):843s-847s. View on PubMed
288. Levine JD, Collier DH, Basbaum AI, Moskowitz MA, Helms CA. Hypothesis: the nervous system may contribute to the pathophysiology of rheumatoid arthritis. J Rheumatol. 1985 Jun; 12(3):406-11. View on PubMed
289. Levine JD, Dardick SJ, Basbaum AI, Scipio E. Reflex neurogenic inflammation. I. Contribution of the peripheral nervous system to spatially remote inflammatory responses that follow injury. J Neurosci. 1985 May; 5(5):1380-6. View on PubMed
290. Lee HS, Basbaum AI. Immunoreactive pro-enkephalin and prodynorphin products are differentially distributed within the nucleus of the solitary tract of the rat. J Comp Neurol. 1984 Dec 20; 230(4):614-9. View on PubMed
291. Levine JD, Clark R, Devor M, Helms C, Moskowitz MA, Basbaum AI. Intraneuronal substance P contributes to the severity of experimental arthritis. Science. 1984 Nov 02; 226(4674):547-9. View on PubMed
292. Guthrie J, Basbaum AI. Colocalization of immunoreactive proenkephalin and prodynorphin products in medullary neurons of the rat. Neuropeptides. 1984 Nov; 4(6):437-45. View on PubMed
293. Glazer EJ, Ramachandran J, Basbaum AI. Radioimmunocytochemistry using a tritiated goat anti-rabbit second antibody. J Histochem Cytochem. 1984 Jul; 32(7):778-82. View on PubMed
294. Glazer EJ, Basbaum AI. Axons which take up [3H]serotonin are presynaptic to enkephalin immunoreactive neurons in cat dorsal horn. Brain Res. 1984 Apr 30; 298(2):386-91. View on PubMed
295. Basbaum AI, Fields HL. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. Annu Rev Neurosci. 1984; 7:309-38. View on PubMed
296. Moss MS, Basbaum AI. The fine structure of the caudal periaqueductal gray of the cat: morphology and synaptic organization of normal and immunoreactive enkephalin-labeled profiles. Brain Res. 1983 Dec 19; 289(1-2):27-43. View on PubMed
297. Glazer EJ, Basbaum AI. Opioid neurons and pain modulation: an ultrastructural analysis of enkephalin in cat superficial dorsal horn. Neuroscience. 1983 Oct; 10(2):357-76. View on PubMed
298. Moss MS, Basbaum AI. The peptidergic organization of the cat periaqueductal gray. II. The distribution of immunoreactive substance P and vasoactive intestinal polypeptide. J Neurosci. 1983 Jul; 3(7):1437-49. View on PubMed
299. Moss MS, Glazer EJ, Basbaum AI. The peptidergic organization of the cat periaqueductal gray. I. The distribution of immunoreactive enkephalin-containing neurons and terminals. J Neurosci. 1983 Mar; 3(3):603-16. View on PubMed
300. Basbaum AI, Glazer EJ. Immunoreactive vasoactive intestinal polypeptide is concentrated in the sacral spinal cord: a possible marker for pelvic visceral afferent fibers. Somatosens Res. 1983; 1(1):69-82. View on PubMed
301. Basbaum AI, Glazer EJ, Lord BA. Simultaneous ultrastructural localization of tritiated serotonin and immunoreactive peptides. J Histochem Cytochem. 1982 Aug; 30(8):780-4. View on PubMed
302. Grossman ML, Basbaum AI, Fields HL. Afferent and efferent connections of the rat tail flick reflex (a model used to analyze pain control mechanisms). J Comp Neurol. 1982 Mar 20; 206(1):9-16. View on PubMed
303. Abols IA, Basbaum AI. Afferent connections of the rostral medulla of the cat: a neural substrate for midbrain-medullary interactions in the modulation of pain. J Comp Neurol. 1981 Sep 10; 201(2):285-97. View on PubMed
304. Glazer EJ, Basbaum AI. Immunohistochemical localization of leucine-enkephalin in the spinal cord of the cat: enkephalin-containing marginal neurons and pain modulation. J Comp Neurol. 1981 Mar 01; 196(3):377-89. View on PubMed
305. Basbaum AI. Descending control of pain transmission: possible serotonergic-enkephalinergic interactions. Adv Exp Med Biol. 1981; 133:177-89. View on PubMed
306. Moss MS, Glazer EJ, Basbaum AI. Enkephalin-immunoreactive perikarya in the cat raphe dorsalis. Neurosci Lett. 1981 Jan 01; 21(1):33-7. View on PubMed
307. Glazer EJ, Steinbusch H, Verhofstad A, Basbaum AI. Serotonin neurons in nucleus raphe dorsalis and paragigantocellularis of the cat contain enkephalin. J Physiol (Paris). 1981; 77(2-3):241-5. View on PubMed
308. Glazer EJ, Basbaum AI. Leucine enkephalin: localization in and axoplasmic transport by sacral parasympathetic preganglionic neurons. Science. 1980 Jun 27; 208(4451):1479-81. View on PubMed
309. Barton C, Basbaum AI, Fields HL. Dissociation of supraspinal and spinal actions of morphine: a quantitative evaluation. Brain Res. 1980 Apr 28; 188(2):487-98. View on PubMed
310. Basbaum AI, Fields HL. The origin of descending pathways in the dorsolateral funiculus of the spinal cord of the cat and rat: further studies on the anatomy of pain modulation. J Comp Neurol. 1979 Oct 01; 187(3):513-31. View on PubMed
311. Abols IA, Basbaum AI. The posterior pretectal nucleus: evidence for a direct projection to the inferior olive of the cat. Neurosci Lett. 1979 Jul; 13(2):111-6. View on PubMed
312. Giesler GJ, Menétrey D, Basbaum AI. Differential origins of spinothalamic tract projections to medial and lateral thalamus in the rat. J Comp Neurol. 1979 Mar 01; 184(1):107-26. View on PubMed
313. Wong RK, Prince DA, Basbaum AI. Intradendritic recordings from hippocampal neurons. Proc Natl Acad Sci U S A. 1979 Feb; 76(2):986-90. View on PubMed
314. Basbaum AI, Fields HL. Endogenous pain control mechanisms: review and hypothesis. Ann Neurol. 1978 Nov; 4(5):451-62. View on PubMed
315. Basbaum AI, Clanton CH, Fields HL. Three bulbospinal pathways from the rostral medulla of the cat: an autoradiographic study of pain modulating systems. J Comp Neurol. 1978 Mar 15; 178(2):209-24. View on PubMed
316. Fields HL, Basbaum AI. Brainstem control of spinal pain-transmission neurons. Annu Rev Physiol. 1978; 40:217-48. View on PubMed
317. Fields HL, Basbaum AI, Clanton CH, Anderson SD. Nucleus raphe magnus inhibition of spinal cord dorsal horn neurons. Brain Res. 1977 May 13; 126(3):441-53. View on PubMed
318. Anderson SD, Basbaum AI, Fields HL. Response of medullary raphe neurons to peripheral stimulation and to systemic opiates. Brain Res. 1977 Mar 11; 123(2):363-8. View on PubMed
319. Basbaum AI, Marley NJE, O'Keefe J, Clanton CH. Reversal of morphine and stimulus-produced analgesia by subtotal spinal cord lesions. Pain. 1977 Feb; 3(1):43-56. View on PubMed
320. Basbaum AI, Clanton CH, Fields HL. Opiate and stimulus-produced analgesia: functional anatomy of a medullospinal pathway. Proc Natl Acad Sci U S A. 1976 Dec; 73(12):4685-8. View on PubMed
321. Basbaum AI, Wall PD. Chronic changes in the response of cells in adult cat dorsal horn following partial deafferentation: the appearance of responding cells in a previously non-responsive region. Brain Res. 1976 Nov 05; 116(2):181-204. View on PubMed
322. Millar J, Basbaum AI, Wall PD. Restructuring of the somatotopic map and appearance of abnormal neuronal activity in the gracile nucleus after partial deafferentation. Exp Neurol. 1976 Mar; 50(3):658-72. View on PubMed
323. Fields HL, Anderson SD, Clanton CH, Basbaum AI. Nucleus raphe magnus: a common mediator of opiate- and stimulus-produced analgesia. Trans Am Neurol Assoc. 1976; 101:208-10. View on PubMed
324. Millar J, Basbaum AI. Topography of the projection of the body surface of the cat to cuneate and gracile nuclei. Exp Neurol. 1975 Oct; 49(1 Pt 1):281-90. View on PubMed
325. Wall PD, Waxman S, Basbaum AI. Ongoing activity in peripheral nerve: injury discharge. Exp Neurol. 1974 Dec; 45(3):576-89. View on PubMed
326. Basbaum AI. Effects of central lesions on disorders produced by multiple dorsal rhizotomy in rats. Exp Neurol. 1974 Mar; 42(3):490-501. View on PubMed
327. Basbaum AI. Conduction of the effects of noxious stimulation by short-fiber multisynaptic systems of the spinal cord in the rat. Exp Neurol. 1973 Sep; 40(3):699-716. View on PubMed
328. Basbaum AI, Hand PJ. Projections of cervicothoracic dorsal roots to the cuneate nucleus of the rat, with observations on cellular "bricks". J Comp Neurol. 1973 Apr 01; 148(3):347-59. View on PubMed